Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804832 | 0.88 | CYP2C19 (0.62) | CYP2C19CYP2D6CYP2C9RECQLOPRM1 | |
| Hydrochloric Acid SCHEMBL5967107 | 0.86 | CYP2C19 (0.61) | CYP2C19CYP2D6CYP2C9RECQLOPRM1 | |
| SCHEMBL23901561 | 0.84 | CYP2C19 (0.64) | CYP2C19CYP2D6CYP2C9RECQLMEN1 | |
| SCHEMBL2517347 | 0.82 | L3MBTL1 (0.51) | CYP2C19CYP2D6CYP2C9RECQLMEN1 | |
| SCHEMBL2517348 | 0.82 | L3MBTL1 (0.51) | CYP2C19CYP2D6CYP2C9RECQLMEN1 | |
| SCHEMBL4988804 | 0.81 | SMN1; SMN2 (0.62) | CYP2C19CYP2D6CYP2C9RECQLMEN1 | |
| SCHEMBL27723672 | 0.81 | CYP2D6 (0.58) | CYP2C19CYP2D6CYP2C9RECQLOPRM1 | |
| SCHEMBL4988824 | 0.81 | SMN1; SMN2 (0.62) | CYP2C19CYP2D6CYP2C9RECQLMEN1 | |
| SCHEMBL6136702 | 0.81 | SMN1; SMN2 (0.62) | CYP2C19CYP2D6CYP2C9RECQLMEN1 | |
| SCHEMBL27723671 | 0.81 | CYP2D6 (0.58) | CYP2C19CYP2D6CYP2C9RECQLOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311259-B1 | PHARMACEUTICAL COMPOSITION COMPRISING AN ESTER OF 5-AMINOLEVULINIC ACID AS PHOTOCHEMOTHERAPEUTIC AGENT AND A MUCOADHESIVE AGENT | PHOTOCURE ASA (NO) | 2005-06-15 | — | — | EP | claimed |