Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 14/20 | 0.36 |
| ▸ | CTSA | P10619 | 4/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271280 | 1.00 | PTPRZ1 (0.39) | PTPRZ1CD274CTSAPDCD1PPARD | |
| SCHEMBL6231277 | 0.90 | PTPRZ1 (0.41) | PTPRZ1CD274CTSAPDCD1PPARD | |
| SCHEMBL6237287 | 0.89 | CTSA (0.42) | CD274CTSAPDCD1PPARD | |
| SCHEMBL6253469 | 0.89 | CTSA (0.42) | CD274CTSAPDCD1PPARD | |
| SCHEMBL6232104 | 0.80 | PTPRZ1 (0.42) | PTPRZ1CD274CTSAPDCD1PPARD | |
| SCHEMBL6256021 | 0.80 | PTPRZ1 (0.42) | PTPRZ1CD274CTSAPDCD1PPARD | |
| SCHEMBL6271288 | 0.78 | PTPRZ1 (0.38) | PTPRZ1CD274PDCD1PPARD | |
| SCHEMBL6234948 | 0.78 | PTPRZ1 (0.38) | PTPRZ1CD274PDCD1PPARD | |
| SCHEMBL6231278 | 0.78 | PTPRZ1 (0.41) | PTPRZ1CD274PPARD | |
| SCHEMBL6235514 | 0.77 | CD274 (0.40) | CD274CTSAPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |