Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 3/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253469 | 1.00 | CTSA (0.42) | CTSACD274ALDH1A1PDCD1TMEM97 | |
| SCHEMBL6271280 | 0.89 | PTPRZ1 (0.39) | CTSACD274PDCD1PPARD | |
| SCHEMBL6234945 | 0.89 | PTPRZ1 (0.39) | CTSACD274PDCD1PPARD | |
| SCHEMBL6236045 | 0.88 | CTSA (0.43) | CTSACD274PDCD1CASRPPARG | |
| SCHEMBL6236043 | 0.88 | CTSA (0.43) | CTSACD274PDCD1CASRPPARG | |
| SCHEMBL6235514 | 0.79 | CD274 (0.40) | CTSACD274PDCD1KMT2A | |
| SCHEMBL6236047 | 0.79 | CTSA (0.45) | CTSACD274CASR | |
| SCHEMBL6233511 | 0.79 | CTSA (0.42) | CTSACD274PDCD1MAOBKMT2A | |
| SCHEMBL6231277 | 0.78 | PTPRZ1 (0.41) | CTSACD274PDCD1PPARD | |
| SCHEMBL6237290 | 0.77 | TMEM97 (0.36) | CTSACD274TMEM97MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |