Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.57 |
| ▸ | MAOB | P27338 | 4/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19281401 | 0.85 | KDM1A (0.55) | KDM1AMAOBIDO1HSD17B1HSD17B2 | |
| SCHEMBL1416558 | 0.85 | KDM1A (0.61) | KDM1AMAOBIDO1KMOMAOA | |
| SCHEMBL29995340 | 0.85 | KDM1A (0.55) | KDM1AMAOBIDO1HSD17B1HSD17B2 | |
| SCHEMBL6236148 | 0.82 | KDM1A (0.58) | KDM1AMAOBIDO1KMOMAOA | |
| SCHEMBL6234240 | 0.81 | KDM1A (0.64) | KDM1AMAOBIDO1KMOMAOA | |
| SCHEMBL27956294 | 0.81 | HSD17B1 (0.63) | KDM1AMAOBIDO1HSD17B1HSD17B2 | |
| SCHEMBL10093051 | 0.81 | DHODH (0.57) | KDM1AMAOBIDO1KMOMAOA | |
| SCHEMBL6240438 | 0.81 | KDM1A (0.57) | KDM1AMAOBIDO1KMOMAOA | |
| SCHEMBL19992829 | 0.81 | KDM1A (0.57) | KDM1AMAOBIDO1KMOMAOA | |
| SCHEMBL4591309 | 0.80 | MAOB (0.53) | KDM1AMAOBIDO1KMOMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |