Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.48 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761994 | 0.82 | ALDH1A1 (0.59) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL24476682 | 0.79 | AR (0.54) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL1608900 | 0.79 | AR (0.69) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL2614475 | 0.79 | AR (0.69) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL1343373 | 0.78 | ALDH1A1 (0.55) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL286644 | 0.78 | AR (0.53) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL13560245 | 0.78 | AR (0.53) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL551293 | 0.78 | AR (0.53) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL7668281 | 0.78 | AR (0.53) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL1642615 | 0.78 | KDM4E (0.79) | ARALDH1A1KDM4EUSP2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606268-A1 | HETEROCYCLIC KINASE INHIBITORS | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004076424-A1 | HETEROCYCLIC KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2004-09-10 | — | — | WO | disclosed |