Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14777479 | 0.85 | LMNA (0.52) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL2531522 | 0.84 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL3382609 | 0.84 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9118888 | 0.83 | LMNA (0.62) | LMNACYP2C19HIF1A | |
| SCHEMBL622562 | 0.81 | LMNA (0.48) | LMNACYP2C19HIF1AEGFRSRC | |
| Iofratol SCHEMBL3148360 | 0.81 | LMNA (0.83) | LMNACYP2C19HIF1AEGFRSRC | |
| Iofratol SCHEMBL381161 | 0.81 | LMNA (0.83) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9526337 | 0.79 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8978095 | 0.79 | LMNA (0.46) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9761063 | 0.79 | LMNA (0.46) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883597-B1 | PROCESS FOR THE PURIFICATION OF AN AMINOALCOHOL | BRACCO IMAGING SPA (IT) | 2005-06-01 | — | — | EP | disclosed |
| US-5866719-A | Process for the purification of an aminoalcohol | DIBRA S.P.A. (IT) | 1999-02-02 | — | — | US | disclosed |