Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 10/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235467 | 0.90 | EGFR (0.51) | EGFRERBB2ERBB4 | |
| SCHEMBL6235493 | 0.83 | EGFR (0.54) | EGFRERBB2ERBB4 | |
| SCHEMBL6234138 | 0.83 | EGFR (0.48) | EGFRERBB2ERBB4 | |
| SCHEMBL6236609 | 0.79 | EGFR (0.53) | EGFRERBB2 | |
| SCHEMBL6235774 | 0.78 | ERBB2 (0.65) | EGFRERBB2ERBB4 | |
| SCHEMBL6232961 | 0.76 | ERBB2 (0.51) | EGFRERBB2ERBB4 | |
| Trifluoroacetic Acid SCHEMBL6237996 | 0.74 | EGFR (0.52) | EGFRERBB2ERBB4 | |
| SCHEMBL6240376 | 0.73 | EGFR (0.58) | EGFRERBB2 | |
| SCHEMBL6236186 | 0.73 | EGFR (0.58) | EGFRERBB2 | |
| SCHEMBL6238409 | 0.71 | EGFR (0.65) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |