Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 2/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235428 | 1.00 | CHRM2 (0.58) | CHRM2CHRM4CHRM1CHRM3PTPN2 | |
| SCHEMBL22382749 | 0.86 | SERPINE1 (0.51) | CHRM2CHRM4CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL8113981 | 0.84 | CHRM2 (0.57) | CHRM2CHRM4CHRM1CHRM3PTPN2 | |
| SCHEMBL12898142 | 0.84 | POLB (0.55) | CHRM2CHRM4CHRM1CHRM3PTPN2 | |
| SCHEMBL636680 | 0.83 | PTPN2 (0.56) | CHRM2CHRM4CHRM1CHRM3PTPN2 | |
| SCHEMBL27400395 | 0.82 | PTPN2 (0.70) | CHRM2CHRM4CHRM1CHRM3PTPN2 | |
| SCHEMBL6234235 | 0.81 | POLB (0.55) | CHRM2CHRM4CHRM1CHRM3PTPN2 | |
| SCHEMBL6234232 | 0.81 | POLB (0.55) | CHRM2CHRM4CHRM1CHRM3PTPN2 | |
| SCHEMBL30397957 | 0.81 | CHRM2 (0.51) | CHRM2CHRM4CHRM1CHRM3PTPN2 | |
| SCHEMBL17941243 | 0.81 | PTPN2 (0.68) | CHRM2CHRM4CHRM1CHRM3PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000855-A1 | PROCESS FOR THE PREPARATION OF ATROPISOMERIC ANALOGUES OF 4-AMINOPYRIDINE | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |