Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6234235 | 1.00 | POLB (0.55) | POLBCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL12898142 | 0.85 | POLB (0.55) | POLBCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6235428 | 0.81 | CHRM2 (0.58) | POLBCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6235437 | 0.81 | CHRM2 (0.58) | POLBCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6232576 | 0.81 | CHRM2 (0.53) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL6232578 | 0.81 | CHRM2 (0.53) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL8113981 | 0.80 | CHRM2 (0.57) | POLBCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6232026 | 0.79 | ALDH1A1 (0.47) | CHRM2CHRM4CHRM1CHRM3L3MBTL1 | |
| SCHEMBL6232028 | 0.79 | ALDH1A1 (0.47) | CHRM2CHRM4CHRM1CHRM3L3MBTL1 | |
| SCHEMBL6236146 | 0.78 | CHRM2 (0.57) | CHRM2CHRM4CHRM1CHRM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000855-A1 | PROCESS FOR THE PREPARATION OF ATROPISOMERIC ANALOGUES OF 4-AMINOPYRIDINE | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |