Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037917 | 0.73 | TSHR (0.38) | CYP19A1NPSR1FAAHCYP3A4TP53 | |
| SCHEMBL4041592 | 0.69 | FAAH (0.35) | CYP19A1FAAHCYP3A4TP53TSHR | |
| SCHEMBL18485419 | 0.69 | CYP3A4 (0.39) | NPSR1FAAHCYP3A4TSHRLMNA | |
| SCHEMBL4043279 | 0.67 | FAAH (0.36) | CYP19A1FAAHTP53TSHRGAA | |
| SCHEMBL23812541 | 0.66 | NPSR1 (0.40) | CYP19A1NPSR1FAAHCYP3A4TSHR | |
| SCHEMBL8521913 | 0.66 | CYP3A4 (0.43) | NPSR1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL6930133 | 0.65 | TSHR (0.37) | NPSR1FAAHCYP3A4TSHRLMNA | |
| SCHEMBL18485435 | 0.65 | TSHR (0.37) | NPSR1FAAHCYP3A4TSHRLMNA | |
| SCHEMBL6235471 | 0.65 | CYP19A1 (0.31) | CYP19A1FAAH | |
| SCHEMBL18485441 | 0.63 | HTT (0.40) | NPSR1FAAHCYP3A4TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |