Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.48 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562150 | 0.86 | NR4A2 (0.52) | MAOBNR4A2FFAR1FFAR4S1PR1 | |
| SCHEMBL10566519 | 0.83 | NR4A2 (0.56) | MAOBNR4A2FFAR1FFAR4S1PR1 | |
| SCHEMBL3498840 | 0.82 | NR4A2 (0.71) | MAOBNR4A2FFAR1RXRARXRB | |
| SCHEMBL5512464 | 0.80 | MAOB (0.52) | MAOBNR4A2FFAR1FFAR4PPARD | |
| SCHEMBL6235530 | 0.79 | MAOB (0.55) | MAOBNR4A2FFAR1FFAR4PPARD | |
| SCHEMBL6241934 | 0.78 | POLB (0.56) | MAOBNR4A2FFAR1FFAR4PPARD | |
| SCHEMBL16552376 | 0.77 | MAOB (1.00) | MAOB | |
| SCHEMBL11598621 | 0.77 | NR4A2 (0.54) | MAOBNR4A2PPARDPPARACA2 | |
| Hydrochloric Acid SCHEMBL17923795 | 0.76 | MAOB (0.98) | MAOB | |
| Hydrochloric Acid SCHEMBL17923792 | 0.76 | MAOB (0.98) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |