Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235528 | 0.79 | MAOB (0.62) | MAOBNR4A2ALKBH1FFAR1FFAR4 | |
| SCHEMBL13034130 | 0.79 | GAA (0.49) | MAOBALKBH1LMNAALDH1A1GAA | |
| SCHEMBL6331482 | 0.78 | NR4A2 (0.48) | MAOBNR4A2MAOAALKBH1FFAR1 | |
| SCHEMBL6236731 | 0.77 | MAOB (0.57) | MAOBNR4A2MAOAADAMTS4MMP1 | |
| SCHEMBL5512464 | 0.76 | MAOB (0.52) | MAOBNR4A2ALKBH1FFAR1FFAR4 | |
| SCHEMBL1151268 | 0.76 | MAOB (0.50) | MAOBNR4A2MAOAALKBH1FFAR1 | |
| SCHEMBL365034 | 0.76 | SCN9A (0.54) | MAOBNR4A2MAOAPTGER4ADAMTS4 | |
| SCHEMBL76135 | 0.76 | LMNA (0.64) | PPARALMNAALDH1A1GAAMAPT | |
| SCHEMBL11704258 | 0.75 | NR4A2 (0.76) | MAOBNR4A2MAOANR4A1NR4A3 | |
| SCHEMBL17514520 | 0.74 | NR4A2 (0.44) | MAOBNR4A2ALKBH1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |