Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.59 |
| ▸ | MMP2 | P08253 | 2/20 | 0.59 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.45 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.44 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.43 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237246 | 1.00 | PSMD14 (0.59) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL6243942 | 1.00 | PSMD14 (0.59) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL9738872 | 1.00 | PSMD14 (0.59) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL9738866 | 0.90 | PSMD14 (0.60) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL9836097 | 0.90 | PSMD14 (0.60) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL9738875 | 0.89 | PLA2G1B (0.56) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL9836109 | 0.89 | PLA2G1B (0.56) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL6235250 | 0.87 | LPAR5 (0.68) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL6234843 | 0.87 | LPAR5 (0.68) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL6236700 | 0.87 | LPAR5 (0.68) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756633-B1 | METHOD AND KITS FOR PROCESSING MYCOBACTERIA AND MYCOLIC ACID CONTAINING BACTERIA | INTEGRATED RES TECHNOLOGY LLC (US) | 2005-06-08 | — | — | EP | claimed |
| US-6004771-A | EXTRACTED MYCOBACTERIAL SAMPLE IS SUITABLE FOR DETECTION BY CULTURE AND AMPLIFICATION | INTEGRATED RESEARCH TECHNOLOGY, LLC (US) | 1999-12-21 | — | — | US | disclosed |
| US-5658749-A | DECREASING THE BUOYANCY OF MICROORGANISMS CONTAINING MYCOLIC ACID-LIKE STRUCTURES IN THE OUTER MEMBRANE USING A SOLUTION OF AN SB-18-LIKE OR ROD-LIKE DETERGENT; AMPHOTERIC SURFACTANTS; MEDICAL DIAGNOSIS; CULTURES; AMPLIFICATION | CORNING CLINICAL LABORATORIES, INC. (US) | 1997-08-19 | — | — | US | disclosed |