Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235554 | 0.90 | CHRM2 (0.33) | CHRM4CHRM2CHRM3PPARGPPARA | |
| SCHEMBL6241528 | 0.89 | SYK (0.33) | CHRM4CHRM2CHRM3PKMPPARG | |
| SCHEMBL4870741 | 0.82 | SYK (0.37) | CHRM4CNR2CNR1PKMSYK | |
| SCHEMBL4862738 | 0.82 | SYK (0.37) | CHRM4CNR2CNR1PKMSYK | |
| SCHEMBL4870425 | 0.81 | SYK (0.38) | CHRM4PKMSYKPRMT5WDR77 | |
| SCHEMBL4868524 | 0.76 | SYK (0.38) | CHRM4CNR2CNR1CHRM2CHRM3 | |
| SCHEMBL4581881 | 0.75 | PRMT5 (0.32) | PKMPRMT5WDR77 | |
| SCHEMBL4581885 | 0.75 | PRMT5 (0.32) | PKMPRMT5WDR77 | |
| SCHEMBL6232490 | 0.73 | SYK (0.37) | CHRM4SYKPRMT5WDR77 | |
| SCHEMBL4869547 | 0.73 | SYK (0.37) | CHRM4CHRM2CHRM3SYKPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005456-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-01-20 | — | — | WO | disclosed |