Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 4/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | RET | P07949 | 2/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12424419 | 0.81 | GPR119 (0.55) | SMOCHRM4L3MBTL1ALDH1A1PANK3 | |
| SCHEMBL3323867 | 0.80 | SMN1; SMN2 (0.54) | CHRM4LMNATSHRTNFSTAT3 | |
| SCHEMBL2776292 | 0.80 | SLC6A2 (0.55) | CHRM4LMNATSHRL3MBTL1HTT | |
| SCHEMBL13622620 | 0.80 | KCNH2 (0.55) | SMOCHRM4CHRM2CHRM5CHRM1 | |
| SCHEMBL1729285 | 0.77 | CHRM4 (0.57) | CHRM4CHRM2CHRM5CHRM1PANK3 | |
| SCHEMBL10107366 | 0.76 | AVPR1A (0.55) | SMOLMNATSHRTNFSTAT3 | |
| SCHEMBL31442688 | 0.76 | SMO (0.57) | SMOSMN1; SMN2L3MBTL1HTTALDH1A1 | |
| SCHEMBL12099334 | 0.76 | GPR119 (0.55) | SMOCHRM4RETL3MBTL1ALDH1A1 | |
| SCHEMBL9923317 | 0.76 | GPR119 (0.58) | SMOL3MBTL1ALDH1A1PANK3GPR119 | |
| SCHEMBL1347347 | 0.76 | GPR119 (0.55) | SMOL3MBTL1ALDH1A1PANK3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |