SCHEMBL6235894

SCHEMBL6235894

CCCCC[Al](CCCC)CCCC

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
THRB P10828 1/20 0.47
LMNA P02545 3/20 0.40
SLC22A1 O15245 3/20 0.37
SLC22A2 O15244 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
DNM1 Q05193 5/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6694665 1.00 TSHR (0.47) TSHRTHRBLMNASLC22A1SLC22A2
SCHEMBL10595237 0.97 TSHR (0.53) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL11620345 0.97 TSHR (0.53) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL5333466 0.97 TSHR (0.53) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL11174715 0.97 TSHR (0.53) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL4453586 0.97 TSHR (0.53) TSHRTHRBLMNASLC22A1DNM1
Hydrochloric Acid SCHEMBL1885732 0.97 TSHR (0.44) TSHRTHRBLMNASLC22A1SLC22A2
SCHEMBL6697484 0.97 TSHR (0.53) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL50010 0.96 TSHR (0.50) TSHRTHRBLMNASLC22A1SLC22A2
SCHEMBL23040209 0.93 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1055673-B1 CARRIER FOR OLEFIN POLYMERIZATION CATALYSTS COMPRISING AN ALUMINIUM-OXY COMPOUND AND CATALYST COMPONENT IDEMITSU KOSAN CO (JP) 2005-04-27 EP disclosed
US-6562918-B1 A catalyst for olefin polymerization, which is obtained by contacting (A) a compound of a transition metal of Groups 4 to 6 of the Periodic Table, (B) an organoaluminiumoxy compound, and optionally (C) a carrier with each other, and for which IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-05-13 US disclosed
EP-1085025-A1 CATALYST FOR OLEFIN POLYMERIZATION, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING OLEFIN POLYMER Idemitsu Petrochemical Co., Ltd. (JP) 2001-03-21 EP disclosed
EP-1055673-A1 ALUMINUMOXY COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING POLYOLEFIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-11-29 EP disclosed
EP-0398439-B1 Solid alpha-olefin polymerization catalyst components MONTELL TECHNOLOGY COMPANY BV (NL) 1997-04-09 EP disclosed
EP-0470171-B1 POLYMERIZATION PROCESS AND CATALYST SHELL OIL CO (US) 1996-12-04 EP disclosed
EP-0500530-B1 CATALYST COMPONENT FOR MAKING PRIMARILY ISOTACTIC ELASTOMERIC POLYPROPYLENE OR POLYBUTENE SHELL OIL CO (US) 1996-09-11 EP disclosed
CN-1026003-C Process for manufacturing of catalyst composition used in olefin polymerization SHELL OIL CO (US) 1994-09-28 CN disclosed
EP-0297824-B1 Method for crystallizing magnesium chloride for use in a catalyst composition SHELL OIL CO (US) 1994-08-17 EP disclosed
US-5328877-A Halogenation a magnesium compound, teaction with titanium tetrahalide to form titanium trihalide phenoxy SHELL OIL COMPANY (US) 1994-07-12 US disclosed
US-4710482-A COORDINATION CATALYST WITH HIGH ACTIVITY, SELECTIVITY AND MORPHOLOGY; SHELL OIL COMPANY (US) 1987-12-01 US disclosed
CN-87102435-A The preparation of olefin polymerization catalyst component 1987-11-18 CN disclosed
EP-0236082-A2 Preparation of olefin polymerization catalyst component SHELL OIL COMPANY (US) 1987-09-09 EP disclosed
US-4548915-A ABSORPTION OF MINERAL OIL INTO CATALYST PORES-STORAGE STABILITY SHELL OIL COMPANY (US) 1985-10-22 US disclosed
EP-0029623-B1 PREPARATION OF CATALYST COMPONENTS AND POLYMERIZATION OF OLEFINS EMPLOYING SUCH CATALYST COMPONENTS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-06-13 EP disclosed
US-4419501-A COORDINATION CATALYSTS SHELL OIL COMPANY (US) 1983-12-06 US disclosed
US-4414132-A Olefin polymerization catalyst compositions and a process for the polymerization of olefins employing such compositions SHELL OIL COMPANY (US) 1983-11-08 US disclosed
US-4393182-A ORGANOALUMINUM COMPOUND, ELECTRON DONOR SHELL OIL COMPANY (US) 1983-07-12 US disclosed
US-4343721-A Olefin polymerization catalyst components and polymerization process SHELL OIL COMPANY (US) 1982-08-10 US disclosed
EP-0029623-A1 Preparation of catalyst components and polymerization of olefins employing such catalyst components SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1981-06-03 EP disclosed