Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235894 | 1.00 | TSHR (0.47) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL10595237 | 0.97 | TSHR (0.53) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL11620345 | 0.97 | TSHR (0.53) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL5333466 | 0.97 | TSHR (0.53) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL11174715 | 0.97 | TSHR (0.53) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL4453586 | 0.97 | TSHR (0.53) | TSHRTHRBLMNASLC22A1DNM1 | |
| Hydrochloric Acid SCHEMBL1885732 | 0.97 | TSHR (0.44) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL6697484 | 0.97 | TSHR (0.53) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL50010 | 0.96 | TSHR (0.50) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL23040209 | 0.93 | TSHR (0.57) | TSHRTHRBLMNASLC22A1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040030051-A1 | Polypropylene having low isotacticity and relatively high melting point | BASELL POLYPROPYLEN GMBH (DE) | 2004-02-12 | — | — | US | disclosed |
| US-20030017939-A1 | Catalyst system for the polymerization of olefins | OKUMURA YOSHIKUNI (DE) | 2003-01-23 | — | — | US | disclosed |
| WO-2002038634-A2 | POLYPROPYLENE HAVING LOW ISOTACTICITY AND RELATIVELY HIGH MELTING POINT | BASELL POLYOLEFINE GMBH (DE) | 2002-05-16 | — | — | WO | disclosed |