Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 17/20 | 0.57 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6004608 | 0.99 | ESR1 (0.58) | ESR1ESR2SSTR2LTA4H | |
| Hydrochloric Acid SCHEMBL6004621 | 0.98 | ESR1 (0.59) | ESR1ESR2SSTR2LTA4H | |
| Hydrochloric Acid SCHEMBL6005752 | 0.93 | ESR1 (0.67) | ESR1ESR2SSTR2LTA4H | |
| Hydrochloric Acid SCHEMBL6004711 | 0.92 | ESR1 (0.56) | ESR1ESR2SSTR2 | |
| Hydrochloric Acid SCHEMBL6004951 | 0.92 | ESR1 (0.68) | ESR1ESR2SSTR2LTA4H | |
| Hydrochloric Acid SCHEMBL6003323 | 0.91 | ESR1 (0.66) | ESR1ESR2SSTR2LTA4H | |
| Hydrochloric Acid SCHEMBL6003314 | 0.91 | ESR1 (0.68) | ESR1ESR2SSTR2LTA4H | |
| Hydrochloric Acid SCHEMBL6003405 | 0.90 | ESR1 (0.66) | ESR1ESR2SSTR2 | |
| SCHEMBL4601699 | 0.89 | ESR1 (0.66) | ESR1ESR2SSTR2LTA4H | |
| Hydrochloric Acid SCHEMBL6005587 | 0.89 | ESR1 (0.68) | ESR1ESR2SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530470-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS CONTAINING A PHENYLSULFONYL GROUP | ELI LILLY AND COMPANY (US) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004009086-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS CONTAINING A PHENYLSULFONYL GROUP | ELI LILLY AND COMPANY (US) | 2004-01-29 | — | — | WO | disclosed |