Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 16/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 16/20 | 0.66 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601380 | 0.94 | ESR1 (0.59) | ESR1ESR2SSTR2 | |
| Hydrochloric Acid SCHEMBL6003323 | 0.93 | ESR1 (0.66) | ESR1ESR2SSTR2LTA4H | |
| Hydrochloric Acid SCHEMBL6003314 | 0.92 | ESR1 (0.68) | ESR1ESR2SSTR2LTA4H | |
| SCHEMBL6232447 | 0.89 | ESR1 (0.57) | ESR1ESR2SSTR2 | |
| SCHEMBL6235937 | 0.89 | ESR1 (0.57) | ESR1ESR2SSTR2LTA4H | |
| Hydrochloric Acid SCHEMBL6004608 | 0.88 | ESR1 (0.58) | ESR1ESR2SSTR2LTA4H | |
| SCHEMBL5706949 | 0.88 | ESR1 (0.58) | ESR1ESR2SSTR2 | |
| Hydrochloric Acid SCHEMBL6003405 | 0.88 | ESR1 (0.66) | ESR1ESR2SSTR2 | |
| Hydrochloric Acid SCHEMBL6005752 | 0.88 | ESR1 (0.67) | ESR1ESR2SSTR2LTA4H | |
| Hydrochloric Acid SCHEMBL6004621 | 0.88 | ESR1 (0.59) | ESR1ESR2SSTR2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200507-A1 | Crystalline Non-Solvated Methanesulfonic Acid Salt of 1-(4-(2-Piperidinylethoxy)Phenoxy)-2-(3-Hydroxyphenyl)-6-Hydroxynaphthalene | ELI LILLY AND COMPANY | 2008-08-21 | — | — | US | disclosed |
| US-20080200507-A1 | Crystalline Non-Solvated Methanesulfonic Acid Salt of 1-(4-(2-Piperidinylethoxy)Phenoxy)-2-(3-Hydroxyphenyl)-6-Hydroxynaphthalene | ELI LILLY AND COMPANY | 2008-08-21 | — | — | US | disclosed |
| US-20080200507-A1 | Crystalline Non-Solvated Methanesulfonic Acid Salt of 1-(4-(2-Piperidinylethoxy)Phenoxy)-2-(3-Hydroxyphenyl)-6-Hydroxynaphthalene | ELI LILLY AND COMPANY | 2008-08-21 | — | — | US | disclosed |
| EP-1912962-A2 | CRYSTALLINE NON-SOLVATED METHANESULFONIC ACID SALT OF 1-(4-(2-PIPERIDINYLETHOXY)PHENOXY)-2-(3-HYDROXYPHENYL)-6-HYDROXYNAPHTHALENE | ELI LILLY AND COMPANY (US) | 2008-04-23 | — | — | EP | disclosed |
| EP-1912962-A2 | CRYSTALLINE NON-SOLVATED METHANESULFONIC ACID SALT OF 1-(4-(2-PIPERIDINYLETHOXY)PHENOXY)-2-(3-HYDROXYPHENYL)-6-HYDROXYNAPHTHALENE | ELI LILLY AND COMPANY (US) | 2008-04-23 | — | — | EP | disclosed |
| EP-1912962-A2 | CRYSTALLINE NON-SOLVATED METHANESULFONIC ACID SALT OF 1-(4-(2-PIPERIDINYLETHOXY)PHENOXY)-2-(3-HYDROXYPHENYL)-6-HYDROXYNAPHTHALENE | ELI LILLY AND COMPANY (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007016139-A3 | CRYSTALLINE NON-SOLVATED METHANESULFONIC ACID SALT OF 1-(4-(2-PIPERIDINYLETHOXY)PHENOXY)-2-(3-HYDROXYPHENYL)-6-HYDROXYNAPHTHALENE | LILLY CO ELI (US) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007016139-A3 | CRYSTALLINE NON-SOLVATED METHANESULFONIC ACID SALT OF 1-(4-(2-PIPERIDINYLETHOXY)PHENOXY)-2-(3-HYDROXYPHENYL)-6-HYDROXYNAPHTHALENE | LILLY CO ELI (US) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007016139-A2 | CRYSTALLINE NON-SOLVATED METHANESULFONIC ACID SALT OF 1-(4-(2-PIPERIDINYLETHOXY)PHENOXY)-2-(3-HYDROXYPHENYL)-6-HYDROXYNAPHTHALENE | ELI LILLY AND COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007016139-A2 | CRYSTALLINE NON-SOLVATED METHANESULFONIC ACID SALT OF 1-(4-(2-PIPERIDINYLETHOXY)PHENOXY)-2-(3-HYDROXYPHENYL)-6-HYDROXYNAPHTHALENE | ELI LILLY AND COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007016139-A2 | CRYSTALLINE NON-SOLVATED METHANESULFONIC ACID SALT OF 1-(4-(2-PIPERIDINYLETHOXY)PHENOXY)-2-(3-HYDROXYPHENYL)-6-HYDROXYNAPHTHALENE | ELI LILLY AND COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200507-A1 | Crystalline Non-Solvated Methanesulfonic Acid Salt of 1-(4-(2-Piperidinylethoxy)Phenoxy)-2-(3-Hydroxyphenyl)-6-Hydroxynaphthalene | MPHOSPH6, HCN2, HCN1 | ESR1 4544/4885ESR2 4681/4885SSTR2 1730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.