Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.54 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | BID | P55957 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.49 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.49 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549755 | 1.00 | MEN1 (0.54) | MEN1KMT2ACYP3A4USP2ALDH1A1 | |
| Tetraethylene Glycol SCHEMBL11000047 | 1.00 | MEN1 (0.54) | MEN1KMT2ACYP3A4USP2ALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL11515451 | 0.98 | MEN1 (0.51) | MEN1KMT2ACYP3A4USP2ALDH1A1 | |
| SCHEMBL10456124 | 0.98 | MEN1 (0.51) | MEN1KMT2ACYP3A4USP2ALDH1A1 | |
| Butoxyethanol SCHEMBL9660780 | 0.95 | MEN1 (0.52) | MEN1KMT2ACYP3A4USP2ALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL10601860 | 0.94 | MEN1 (0.48) | MEN1KMT2ACYP3A4USP2ALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL10601556 | 0.94 | MEN1 (0.48) | MEN1KMT2ACYP3A4USP2ALDH1A1 | |
| 2-Ethoxyethanol SCHEMBL11086807 | 0.93 | BID (0.48) | MEN1KMT2ACYP3A4USP2ALDH1A1 | |
| Ethylene Glycol SCHEMBL11471133 | 0.91 | BID (0.49) | MEN1KMT2ACYP3A4HTTMAPT | |
| SCHEMBL7553689 | 0.89 | LIPG (0.53) | MEN1KMT2ACYP3A4HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206189-B1 | ROTAVIRUS VACCINE FORMULATIONS | MERCK & CO INC (US) | 2005-06-01 | — | — | EP | claimed |