Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 6/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CALML3 | P27482 | 1/20 | 0.33 |
| ▸ | SDHA | P31040 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236407 | 0.84 | MAOB (0.46) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL6208415 | 0.82 | MAOB (0.40) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL6477905 | 0.73 | MAOB (0.56) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL6477003 | 0.72 | MAOB (0.52) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL6209789 | 0.72 | F10 (0.32) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL6478291 | 0.71 | MAOB (0.51) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL6478123 | 0.71 | F10 (0.41) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL7081325 | 0.70 | L3MBTL1 (0.44) | MAOBMAOALMNAUSP30 | |
| SCHEMBL7081327 | 0.70 | L3MBTL1 (0.44) | MAOBMAOALMNAUSP30 | |
| SCHEMBL7163678 | 0.70 | F10 (0.52) | F10MAOBMAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549641-A1 | ANTIMICROBIAL 3.1.0 BICYCLIC OXAZOLIDINONE DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004033451-A1 | ANTIMICROBIAL [3.1.0] BICYCLIC OXAZOLIDINONE DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-04-22 | — | — | WO | disclosed |