SCHEMBL6236497

SCHEMBL6236497

CC(C)CCCCCOC(=O)CCc1ccc(O)c(-c2c(C(C)(C)C)ccc3[nH]nnc23)c1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.36
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
LTB4R Q15722 1/20 0.31
PDE1A P54750 1/20 0.31
PDE1B Q01064 1/20 0.31
PDE1C Q14123 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL539016 0.87 APP (0.35) APPCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL2488006 0.85 APP (0.39) APPMEN1CYP1A2POLBCYP3A4
SCHEMBL6999046 0.82 APP (0.37) APPMEN1CYP1A2POLBCYP3A4
SCHEMBL5084394 0.80 PDE1A (0.34) MEN1KMT2APDE1APDE1BPDE1C
SCHEMBL29494854 0.80 PDE1A (0.34) MEN1KMT2APDE1APDE1BPDE1C
SCHEMBL4638212 0.79 APP (0.49) APPMEN1CYP1A2POLBCYP3A4
SCHEMBL30027701 0.79 APP (0.49) APPMEN1CYP1A2POLBCYP3A4
SCHEMBL3746000 0.76 PDE1A (0.36) APPPDE1APDE1BPDE1C
SCHEMBL30211339 0.74 RARB (0.34) MEN1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL673310 0.74 RARB (0.34) MEN1CYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3194482-B1 USE OF PHOSPHOROUS-CONTAINING ORGANIC OXYIMIDES AS FLAME RETARDANTS FOR PLASTICS, FLAME-RETARDANT PLASTIC COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF, MOULDED PART, PAINT AND COATINGS FRAUNHOFER GES FORSCHUNG (DE) 2024-05-08 EP disclosed
EP-3710424-B1 COMPOUNDS HAVING A STABILIZING EFFECT, METHOD FOR PRODUCING SAID COMPOUNDS, COMPOSITION CONTAINING SAID STABILIZING COMPOUNDS, METHOD FOR STABILIZING AN ORGANIC COMPONENT, AND USE OF STABILIZING COMPOUNDS FRAUNHOFER GES FORSCHUNG (DE) 2024-01-03 EP disclosed
EP-3947540-B1 METHOD FOR STABILIZING THERMOPLASTIC RECYCLATES, STABILIZED PLASTIC COMPOSITIONS, AND MOLDING COMPOUNDS AND MOLDED PARTS PRODUCED THEREFROM FRAUNHOFER GES FORSCHUNG (DE) 2023-08-16 EP disclosed
US-20220162422-A1 METHOD FOR STABILIZING THERMOPLASTIC RECYCLATES, STABILIZED PLASTIC COMPOSITIONS, AND MOLDING COMPOUNDS AND MOLDED PARTS PRODUCED THEREFROM Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) 2022-05-26 US disclosed
EP-2978804-A1 USE OF ORGANIC OXY IMIDES AS FLAME RETARDANTS FOR PLASTICS AND FLAME-RETARDANT PLASTICS COMPOSITION AND MOULDINGS PRODUCED THEREFROM Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2016-02-03 EP disclosed
WO-2014154636-A1 USE OF ORGANIC OXY IMIDES AS FLAME RETARDANTS FOR PLASTICS AND FLAME-RETARDANT PLASTICS COMPOSITION AND MOULDINGS PRODUCED THEREFROM Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2014-10-02 WO disclosed
EP-1532195-A1 METHOD OF UNIFORMLY DISTRIBUTING A SUBSTANCE IN A SUBSTRATE Clariant GmbH (DE) 2005-05-25 EP disclosed
WO-2004009682-A1 METHOD OF UNIFORMLY DISTRIBUTING A SUBSTANCE IN A SUBSTRATE CLARIANT GMBH (DE) 2004-01-29 WO disclosed
US-20020156162-A1 Stabilizer combination for the rotomolding process STADLER URS LEO (US) 2002-10-24 US disclosed
EP-0591102-B1 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers CIBA SC HOLDING AG (CH) 2000-10-18 EP disclosed
EP-0912531-A1 POLYOXYALKENE SUBSTITUTED AND BRIDGED TRIAZINE, BENZOTRIAZOLE AND BENZOPHENONE DERIVATIVES AS UV ABSORBERS Ciba SC Holding AG (CH) 1999-05-06 EP disclosed
WO-1998003489-A1 POLYOXYALKENE SUBSTITUTED AND BRIDGED TRIAZINE, BENZOTRIAZOLE AND BENZOPHENONE DERIVATIVES AS UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-01-29 WO disclosed
EP-0591102-A1 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1994-04-06 EP disclosed