Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3746000 | 0.88 | PDE1A (0.36) | APPPDE1APDE1BPDE1CP2RY10 | |
| SCHEMBL5084394 | 0.86 | PDE1A (0.34) | PDE1APDE1BPDE1CMEN1KMT2A | |
| SCHEMBL29494854 | 0.86 | PDE1A (0.34) | PDE1APDE1BPDE1CMEN1KMT2A | |
| SCHEMBL6236497 | 0.85 | APP (0.36) | APPPDE1APDE1BPDE1CCYP3A4 | |
| SCHEMBL6999046 | 0.83 | APP (0.37) | APPPDE1APDE1BPDE1CCYP3A4 | |
| SCHEMBL539016 | 0.83 | APP (0.35) | APPPDE1APDE1BPDE1CCYP3A4 | |
| SCHEMBL29565142 | 0.77 | ALDH1A1 (0.38) | MEN1KMT2AP2RY10ALDH1A1KDM4E | |
| SCHEMBL28093559 | 0.77 | MET (0.32) | POLBTSHRLTB4RTDP1 | |
| SCHEMBL6278572 | 0.77 | ALDH1A1 (0.38) | MEN1KMT2AP2RY10ALDH1A1KDM4E | |
| SCHEMBL2934860 | 0.75 | APP (0.34) | APPTSHRLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379643-A1 | LAYERED SILICATE FLAME RETARDANT COMPOSITIONS | BASF SE (DE) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010069835-A1 | LAYERED SILICATE FLAME RETARDANT COMPOSITIONS | BASF SE (DE) | 2010-06-24 | — | — | WO | disclosed |