Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663553 | 0.74 | ALDH1A1 (0.51) | HPGDALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL11761142 | 0.73 | NPC1 (0.82) | HPGDALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL9416606 | 0.73 | NPC1 (0.82) | HPGDALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL20804653 | 0.71 | NPC1 (0.70) | HPGDALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL24576223 | 0.70 | NPC1 (0.71) | HPGDALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL16562180 | 0.70 | ALDH1A1 (0.69) | HPGDALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL1695235 | 0.69 | NPC1 (0.66) | HPGDALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL15514376 | 0.69 | ALDH1A1 (0.65) | HPGDALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL2721206 | 0.69 | ALDH1A1 (0.65) | HPGDALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL885045 | 0.69 | SMN1; SMN2 (0.69) | HPGDALDH1A1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537090-A1 | CHROMONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-08 | — | — | EP | claimed |
| WO-2004014880-A1 | CHROMONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | claimed |