Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5584501 | 0.88 | HTR1A (0.59) | HTR1ASLC6A4DRD2DRD4ADRB2 | |
| SCHEMBL5585160 | 0.88 | HTR1A (0.59) | HTR1ASLC6A4DRD2DRD4ADRB2 | |
| SCHEMBL6235663 | 0.85 | HTR1A (0.48) | HTR1ASLC6A4DRD2DRD4 | |
| SCHEMBL5584230 | 0.84 | HTR1A (0.60) | HTR1ASLC6A4DRD2DRD4ADRB2 | |
| SCHEMBL5584614 | 0.84 | HTR1A (0.60) | HTR1ASLC6A4DRD2DRD4ADRB2 | |
| SCHEMBL5584233 | 0.84 | HTR1A (0.60) | HTR1ASLC6A4DRD2DRD4ADRB2 | |
| SCHEMBL5584858 | 0.83 | HTR1A (0.59) | HTR1ASLC6A4DRD2DRD4ADRB2 | |
| SCHEMBL6234726 | 0.83 | HTR1A (0.49) | HTR1ASLC6A4DRD2DRD4 | |
| SCHEMBL6235576 | 0.83 | HTR1A (0.47) | HTR1ASLC6A4DRD2DRD4 | |
| SCHEMBL6236958 | 0.83 | HTR1A (0.46) | HTR1ASLC6A4DRD2DRD4ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188747-B1 | PHENOXYPROPYLAMINE COMPOUNDS | MITSUBISHI PHARMA CORP (JP) | 2005-09-07 | — | — | EP | claimed |