SCHEMBL6236759

SCHEMBL6236759

C1=CC2CC1C1C2C2C3C=CC(C3)C12

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 1/20 0.33
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6240119 1.00 ALDH1A1 (0.36) ALDH1A1TDP1CYP3A4MAPT
SCHEMBL19689425 0.83 ALDH1A1 (0.40) ALDH1A1
SCHEMBL959523 0.81 ALDH1A1 (0.38) ALDH1A1
SCHEMBL12546419 0.78 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL959182 0.78 ALDH1A1 (0.42) ALDH1A1
SCHEMBL13685018 0.78 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL19689429 0.78 ALDH1A1 (0.36) ALDH1A1
SCHEMBL145668 0.75
SCHEMBL9254176 0.75 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL5011996 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12180385-B2 Shelf life stable and improved mass polymerizable polycyclic-olefinic compositions PROMERYS, LLC (US) 2024-12-31 US claimed
US-11845880-B2 Polycyclic-olefinic compositions for low-loss films having improved thermal properties PROMERUS, LLC (US) 2023-12-19 US claimed
US-20220135832-A1 SHELF LIFE STABLE AND IMPROVED MASS POLYMERIZABLE POLYCYCLIC-OLEFINIC COMPOSITIONS PROMERUS, LLC (US) 2022-05-05 US claimed
US-20220135831-A1 POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES PROMERUS, LLC (US) 2022-05-05 US claimed
EP-4744462-A1 COMPOSITION Merck Patent GmbH (DE) 2026-05-20 EP disclosed
EP-4605438-A1 COMPOSITION Merck Patent GmbH (DE) 2025-08-27 EP disclosed
WO-2025012183-A1 COMPOSITION MERCK PATENT GMBH (DE) 2025-01-16 WO disclosed
US-12180385-B2 Shelf life stable and improved mass polymerizable polycyclic-olefinic compositions PROMERYS, LLC (US) 2024-12-31 US disclosed
EP-4437027-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2024-10-02 EP disclosed
WO-2024083874-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-04-25 WO disclosed
US-11845880-B2 Polycyclic-olefinic compositions for low-loss films having improved thermal properties PROMERUS, LLC (US) 2023-12-19 US disclosed
WO-2023189302-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND OPTICAL MEMBER 日本ゼオン株式会社 2023-10-05 WO disclosed
US-6538087-B2 (hetero)polycyclic polymer PROMERUS, LLC 2003-03-25 US disclosed
US-20020103317-A1 Polymeric compositions for forming optical waveguides; optical waveguides formed therefrom; and methods for making same SUMITOMO BAKELITE CO., LTD. (JP) 2002-08-01 US disclosed
US-20020064896-A1 Optical waveguides and methods for making the same 3M INNOVATIVE PROPERTIES COMPANY 2002-05-30 US disclosed
US-6350832-B1 CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION THE B. F. GOODRICH COMPANY 2002-02-26 US disclosed
US-6350832-B1 CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION THE B. F. GOODRICH COMPANY 2002-02-26 US disclosed
CN-1333788-A In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes GOODRICH CO B F (US) 2002-01-30 CN disclosed
EP-1155057-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES The B.F.Goodrich Co. (US) 2001-11-21 EP disclosed
WO-2000034344-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES THE B.F.GOODRICH COMPANY (US) 2000-06-15 WO disclosed