SCHEMBL6236869

SCHEMBL6236869

CC(C)=CCCC(C)C(C(=O)O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.48
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TSHR P16473 3/20 0.40
ALOX15 P16050 2/20 0.40
ALDH1A1 P00352 1/20 0.40
KMT2A Q03164 1/20 0.39
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
KDM4E B2RXH2 1/20 0.38
PTGS2 P35354 2/20 0.38
MAPT P10636 2/20 0.37
RECQL P46063 2/20 0.37
ICMT O60725 1/20 0.37
GMNN O75496 1/20 0.37
TRPA1 O75762 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6237736 0.78 CYP2D6 (0.57) CYP2D6KMT2ALMNAPOLBAPAF1
SCHEMBL4226867 0.76 ALOX15 (0.45) ATMTDP1L3MBTL1TSHRALOX15
SCHEMBL23872457 0.74 CYP2D6 (0.61) CYP2D6KMT2ALMNAPOLBHSD17B10
SCHEMBL4921518 0.74 CYP2D6 (0.61) CYP2D6KMT2ALMNAPOLBHSD17B10
SCHEMBL28171482 0.74 CYP2D6 (0.61) CYP2D6KMT2APTGS2TRPA1LMNA
SCHEMBL499471 0.74 CYP2D6 (0.61) CYP2D6KMT2ALMNAPOLBHSD17B10
SCHEMBL28393580 0.74 CYP2D6 (0.52) CYP2D6ALDH1A1POLB
SCHEMBL11269397 0.74 KDM4E (0.37) ATMTDP1L3MBTL1TSHRALOX15
SCHEMBL14359738 0.73 CYP2D6 (0.50) CYP2D6TSHRALDH1A1KMT2AMAPT
SCHEMBL23411628 0.73 ATM (0.39) CYP2D6ATMTDP1L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005012210-A2 ANTIMICROBIAL ACTIVE PREPARATIONS CONTAINING TERPENE DERIVATIVES DR. ANDRE RIEKS - LABOR FÜR ENZYMTECHNOLOGIE GMBH (DE) 2005-02-10 WO disclosed