SCHEMBL6236992

SCHEMBL6236992

COc1cc(O)c(O)c(C(=O)OC(C)C)c1OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.49
CA1 P00915 5/20 0.49
CA2 P00918 5/20 0.49
CA7 P43166 5/20 0.49
CA9 Q16790 5/20 0.49
CA14 Q9ULX7 5/20 0.49
TPMT P51580 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ABCG2 Q9UNQ0 1/20 0.41
HTT P42858 1/20 0.41
PRKCI P41743 1/20 0.40
PRKCZ Q05513 1/20 0.40
PTGS2 P35354 1/20 0.40
ALOX5 P09917 3/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
FLT3 P36888 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1590793 0.78 TPMT (0.56) CA12CA1CA2CA7CA9
SCHEMBL6231790 0.78 CA12 (0.45) CA12CA1CA2CA7CA9
SCHEMBL6233285 0.76 KDM4E (0.54) ALOX5CYP3A4MAPT
SCHEMBL6233829 0.76 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL27921550 0.75 KMT2A (0.60) CA12CA1CA2CA7CA9
SCHEMBL6235773 0.75 ESR1 (0.43) CA12CA1CA2CA7CA9
SCHEMBL6236702 0.74 ESR1 (0.56) ALOX5
SCHEMBL6232529 0.72 CA1 (0.53) CA12CA1CA2CA7CA9
SCHEMBL25142353 0.71 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL13229026 0.71 CA1 (0.77) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed