SCHEMBL1590793

SCHEMBL1590793

COc1cc(O)c(O)c(C(=O)O)c1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 4/20 0.56
PTGS2 P35354 1/20 0.55
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
CA3 P07451 1/20 0.48
PKM P14618 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
MAPT P10636 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
CYP3A4 P08684 2/20 0.46
HPGD P15428 2/20 0.46
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30803073 0.85 PTGS2 (0.55) TPMTPTGS2CA12CA1CA2
SCHEMBL4397386 0.83 TPMT (0.58) TPMTPTGS2CA12CA1CA2
SCHEMBL9774171 0.82 TPMT (0.55) TPMTPTGS2CA12CA1CA2
SCHEMBL5587334 0.81 MAPT (0.47) TPMTPTGS2CA12CA1CA2
SCHEMBL5586775 0.79 PTGS2 (0.43) TPMTPTGS2CA12CA1CA2
SCHEMBL6236992 0.78 CA12 (0.49) TPMTPTGS2CA12CA1CA2
Phloroglucinol SCHEMBL28313277 0.76 MAPT (0.54) TPMTPTGS2CA12CA1CA2
SCHEMBL6233285 0.76 KDM4E (0.54) MAPTCYP3A4POLBNPSR1ALOX5
SCHEMBL5587869 0.76 MAPT (0.56) TPMTPTGS2CA12CA1CA7
SCHEMBL11881848 0.76 MAPT (0.56) TPMTPTGS2CA12CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461072-B2 Late transition metal catalysts for olefin oligomerizations EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-06-11 US disclosed
US-7994086-B2 Late transition metal catalysts for olefin oligomerizations EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-09 US disclosed
US-20110092658-A1 Late Transition Metal Catalysts for Olefin Oligomerizations EXXONMOBIL CHEMICAL PATENTS INC. 2011-04-21 US disclosed
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 TPMT 3472/4885PTGS2 3242/4885CA12 2871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.