Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658650 | 0.85 | HTT (0.62) | ALDH1A1HPGDHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL3657694 | 0.84 | HTT (0.59) | ALDH1A1HPGDHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL9450633 | 0.82 | HTT (0.58) | ALDH1A1HPGDHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL864222 | 0.81 | HTT (0.54) | ALDH1A1HPGDHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL8095290 | 0.80 | HTT (0.52) | ALDH1A1HPGDHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL3656048 | 0.79 | HTT (0.59) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL14973545 | 0.79 | KMT2A (0.60) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL3660316 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HPGDHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL9450606 | 0.78 | HTT (0.60) | ALDH1A1HPGDHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL9450597 | 0.77 | KMT2A (0.55) | ALDH1A1HPGDHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238965-B1 | A process for the preparation of 1-(2-dimethylamino-(4-methoxyphenyl)-ethyl)cyclohexanol | COUNCIL SCIENT IND RES (IN) | 2005-06-08 | — | — | EP | disclosed |