Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CALML3 | P27482 | 1/20 | 0.47 |
| ▸ | SDHA | P31040 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237438 | 1.00 | F10 (0.49) | F10KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL6239815 | 0.91 | F10 (0.49) | F10KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL6239827 | 0.90 | F10 (0.48) | F10KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL6239834 | 0.90 | F10 (0.48) | F10KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8308984 | 0.88 | MAOA (0.54) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL6237156 | 0.87 | KDM4E (0.47) | F10KDM4EALDH1A1MAOAMAOB | |
| SCHEMBL6239389 | 0.85 | F10 (0.56) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL6237098 | 0.85 | F10 (0.56) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL6235172 | 0.84 | F10 (0.47) | F10KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL6234972 | 0.84 | F10 (0.47) | F10KDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003087-A2 | OXAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003087-A2 | OXAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2005-01-13 | — | — | WO | disclosed |