Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205137 | 0.79 | AKR1B1 (0.55) | AKR1B1L3MBTL1 | |
| SCHEMBL6205244 | 0.73 | AKR1B1 (0.69) | AKR1B1 | |
| SCHEMBL12018096 | 0.72 | MAPT (0.48) | — | |
| SCHEMBL6206187 | 0.66 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL13577029 | 0.66 | MAPT (0.44) | L3MBTL1 | |
| SCHEMBL6207325 | 0.65 | AKR1B1 (0.53) | AKR1B1 | |
| SCHEMBL6206337 | 0.63 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL6205848 | 0.63 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL3020961 | 0.62 | LMNA (0.56) | — | |
| SCHEMBL6207180 | 0.62 | AKR1B1 (1.00) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236720-B1 | Sulfonyl pyridazinone compounds useful as aldose reductase inhibitors | PFIZER PROD INC (US) | 2005-06-15 | — | — | EP | claimed |