SCHEMBL623765

SCHEMBL623765

[O]C(Br)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL116202 0.71
SCHEMBL948179 0.67
SCHEMBL6244987 0.67
SCHEMBL66165 0.67
SCHEMBL9068419 0.67
SCHEMBL39039 0.67
SCHEMBL342085 0.67
SCHEMBL375023 0.65
SCHEMBL712469 0.65
SCHEMBL11659736 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12036319-B2 Polyvalent sting activating compositions and uses thereof THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-16 US disclosed
WO-2024112397-A1 COMBINATION THERAPIES COMPRISING KRAS INHIBITORS AND SPH2 INHIBITORS HUYABIO INTERNATIONAL, LLC (US) 2024-05-30 WO disclosed
CN-118056309-A Flame-retardant nonaqueous electrolyte and secondary battery using same 国立大学法人京都大学 2024-05-17 CN disclosed
US-20240141084-A1 BIOFOULING RESISTANT COATINGS AND METHODS OF MAKING AND USING THE SAME SILQ TECHNOLOGIES CORPORATION 2024-05-02 US disclosed
US-11964971-B2 Methods and compositions for modulating splicing SKYHAWK THERAPEUTICS, INC. (US) 2024-04-23 US disclosed
EP-4333850-A1 SHP2 INHIBITOR MONOTHERAPY AND USES THEREOF Huyabio International, LLC (US) 2024-03-13 EP disclosed
EP-4334317-A1 COMBINATION THERAPIES COMPRISING SHP2 INHIBITORS AND EGFR TYROSINE KINASE INHIBITORS Huyabio International, LLC (US) 2024-03-13 EP disclosed
EP-4334318-A1 COMBINATION THERAPIES COMPRISING SHP2 INHIBITORS AND PD-1 INHIBITORS Huyabio International, LLC (US) 2024-03-13 EP disclosed
CN-117677619-A Combination therapy comprising an SHP2 inhibitor and a PD-1 inhibitor 沪亚生物国际有限责任公司 2024-03-08 CN disclosed
EP-3568390-B1 SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST (US) 2024-03-06 EP disclosed
EP-1375472-A1 BENZENE COMPOUND AND SALT THEREOF Eisai Co., Ltd. (JP) 2004-01-02 EP disclosed
EP-0878196-B1 KAINIC ACID NEURONOTOXICITY INHIBITORS AND PYRIDOTHIAZINE DERIVATIVES YAMANOUCHI PHARMA CO LTD (JP) 2003-09-03 EP disclosed
EP-0882768-B1 Method for producing of phthalocyanine compound NIPPON CATALYTIC CHEM IND (JP) 2001-12-19 EP disclosed
US-6133258-A PYRIDOTHIAZINE DERIVATIVE; FOR TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS, MULTIPLE SCLEROSIS, PAIN, GLAUCOMA YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 2000-10-17 US disclosed
US-6034236-A REACTING A PHTHALONITRILE WITH A METAL OXIDE IN PRESENCE OF A SULFONIC ACID CATALYST NIPPON SHOKUBAI CO., LTD. (JP) 2000-03-07 US disclosed
US-5998609-A OPTICAL RECORDING MEDIA NIPPON SHOKUBAI CO., LTD. (JP) 1999-12-07 US disclosed
EP-0889097-A1 PHTHALOCYANINE COMPOUNDS, PROCESS FOR PREPARING THE SAME, AND OPTICAL RECORDING MEDIUM MADE USING THE SAME NIPPON SHOKUBAI CO., LTD. (JP) 1999-01-07 EP disclosed
EP-0882768-A2 Method for producing of phthalocyanine compound NIPPON SHOKUBAI CO., LTD. (JP) 1998-12-09 EP disclosed
EP-0878196-A1 KAINIC ACID NEURONOTOXICITY INHIBITORS AND PYRIDOTHIAZINE DERIVATIVES YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1998-11-18 EP disclosed
WO-1997032858-A1 QUINOXALINE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-09-12 WO disclosed