Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623794 | 0.90 | GCK (0.48) | GCKSMN1; SMN2FFAR1 | |
| SCHEMBL623592 | 0.89 | GCK (0.43) | GCKSMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL623795 | 0.76 | GCK (0.55) | GCK | |
| SCHEMBL624659 | 0.75 | GCK (0.51) | GCK | |
| SCHEMBL624752 | 0.72 | GCK (0.56) | GCK | |
| SCHEMBL624737 | 0.71 | GCK (0.57) | GCK | |
| SCHEMBL622614 | 0.71 | GCK (0.58) | GCK | |
| SCHEMBL184595 | 0.70 | GCK (0.63) | GCK | |
| SCHEMBL11972362 | 0.70 | GCK (0.62) | GCK | |
| SCHEMBL185196 | 0.69 | GCK (0.59) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |