Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 6/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623773 | 0.90 | GCK (0.39) | GCKFFAR1SMN1; SMN2 | |
| SCHEMBL623795 | 0.85 | GCK (0.55) | GCK | |
| SCHEMBL623592 | 0.79 | GCK (0.43) | GCKXIAPSMN1; SMN2 | |
| SCHEMBL624752 | 0.73 | GCK (0.56) | GCK | |
| SCHEMBL623517 | 0.69 | GCK (0.69) | GCK | |
| SCHEMBL623850 | 0.69 | GCK (0.65) | GCK | |
| SCHEMBL625244 | 0.68 | GCK (0.71) | GCK | |
| SCHEMBL185029 | 0.68 | GCK (0.77) | GCK | |
| SCHEMBL3762125 | 0.68 | GCK (0.67) | GCK | |
| SCHEMBL185317 | 0.67 | GCK (0.65) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | claimed |