SCHEMBL6237735

SCHEMBL6237735

N#CCC[N]c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 1/20 0.35
MIF P14174 1/20 0.34
TSHR P16473 2/20 0.33
HTT P42858 2/20 0.33
RPS6KA3 P51812 1/20 0.33
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP1B1 Q16678 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6770104 0.87 KMT2A (0.36) KMT2AALDH1A1MEN1MIFTSHR
SCHEMBL12943093 0.78 ALDH1A1 (0.44) KMT2AALDH1A1MEN1MIFTSHR
SCHEMBL6746254 0.78 ALDH1A1 (0.38) KMT2AALDH1A1MEN1HTTCYP1A2
SCHEMBL28495899 0.78 ALDH1A1 (0.44) KMT2AALDH1A1MEN1MIFTSHR
SCHEMBL8029164 0.77 ALDH1A1 (0.50) KMT2AALDH1A1MEN1MIFTSHR
SCHEMBL17028404 0.72 KMT2A (0.53) KMT2AALDH1A1MEN1CYP1A2SMN1; SMN2
SCHEMBL7754354 0.72 ALDH1A1 (0.50) KMT2AALDH1A1MEN1MIFTSHR
SCHEMBL3939354 0.70 ALDH1A1 (0.42) KMT2AALDH1A1MEN1MIFTSHR
SCHEMBL9639842 0.69 ALDH1A1 (0.41) KMT2AALDH1A1MEN1MIFTSHR
SCHEMBL95534 0.69 ALDH1A1 (0.41) KMT2AALDH1A1MEN1MIFTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0385120-B2 Fiber reactive asymmetric dioxazine compounds and their use as fiber reactive dyes SUMITOMO CHEMICAL CO (JP) 2005-06-15 EP disclosed
US-6146430-A Asymmetric dioxazine compound and method for dyeing or printing fiber Material using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-11-14 US disclosed
US-5977358-A Asymmetric dioxazine compounds, intermediate compounds therefor and application of the asymmetric dioxazine compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-02 US disclosed
US-5892006-A CONTAINING S-TRIAZINE RINGS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-04-06 US disclosed
US-5837869-A CHLORINE-FAST DYE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-11-17 US disclosed
US-5735911-A TRIAZINE DYES HAVING GOOD WET AND LIGHT FASTNESS PROPERTIES CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-04-07 US disclosed
US-5612463-A AMINOTRIAZINE DYES CIBA-GEIGY CORPORATION (US) 1997-03-18 US disclosed
US-5486607-A Dioxazine blue dye compound having vinylsulfone type fiber reactive groups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-01-23 US disclosed
US-5451665-A Fibre-reactive dyes containing two halotriazine groups and dye mixtures and their use CIBA-GEIGY CORPORATION (US) 1995-09-19 US disclosed
US-5438137-A Colorfast bright blue dyes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-01 US disclosed
EP-0275022-A2 Triphenodioxazine compounds and dyeing or printing of fiber materials using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-07-20 EP disclosed
EP-0234778-A2 Dioxazine compound having vinylsulfone type fiber reactive group SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-02 EP disclosed
US-4578457-A Reactive mono-azo dyes and the preparation and use thereof CIBA-GEIGY AG (CH) 1986-03-25 US disclosed
US-4246410-A BENZINDOLE DYES OF YELLOW AND RED CIBA -GEIGY AKTIENGESELLSCHAFT (CH) 1981-01-20 US disclosed
US-4246422-A Naphtholactam dyestuffs CIBA-GEIGY AG (CH) 1981-01-20 US disclosed
US-4236007-A YELLOW SHADES ON POLYESTERS CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-11-25 US disclosed
US-4180665-A Substituted 3-benz(cd)indol-2-(1H)-ylidene-furo[2,3-b]quinoxalin-2(3H)one dyestuffs CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1979-12-25 US disclosed
US-4148805-A POLYESTERS, RED, YELLLOW CIBA-GEIGY AG (CH) 1979-04-10 US disclosed
US-4146541-A YELLOW SHADE ON POLYESTERS CIBA-GEIGY AG (CH) 1979-03-27 US disclosed
US-4028323-A WITH A SUBSTITUTED AMINOBENZENE CIBA-GEIGY AG (CH) 1977-06-07 US disclosed