Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12610133 | 0.86 | CTSK (0.39) | CTSKS1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL10324090 | 0.84 | S1PR2 (0.51) | S1PR2S1PR1S1PR3S1PR4SPHK1 | |
| SCHEMBL5454624 | 0.83 | CTSK (0.55) | CTSKS1PR2S1PR1CTSS | |
| SCHEMBL5479821 | 0.83 | CTSK (0.47) | CTSKS1PR2S1PR1S1PR3SPHK1 | |
| SCHEMBL5454618 | 0.83 | CTSK (0.55) | CTSKS1PR2S1PR1CTSS | |
| SCHEMBL5447774 | 0.82 | CTSK (0.52) | CTSKS1PR2S1PR1S1PR3SPHK1 | |
| SCHEMBL16934137 | 0.82 | CTSK (0.52) | CTSKS1PR2S1PR1S1PR3CTSS | |
| SCHEMBL16945658 | 0.82 | CTSK (0.52) | CTSKS1PR2S1PR1S1PR3SPHK1 | |
| SCHEMBL5477122 | 0.82 | CTSK (0.56) | CTSK | |
| SCHEMBL16934135 | 0.82 | CTSK (0.52) | CTSKS1PR2S1PR1S1PR3CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014603-A1 | PHOSPHINANE COMPOUNDS WITH IMMUNOMODULATING ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |