Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371582 | 0.73 | CD274 (0.39) | NR4A2SMN1; SMN2CD274PDCD1ALDH1A1 | |
| SCHEMBL30170212 | 0.72 | CD274 (0.44) | NR4A2CD274PDCD1 | |
| SCHEMBL28594958 | 0.72 | MAPK1 (0.55) | LMNAMMEITGB1ITGA5MAPK1 | |
| SCHEMBL29141118 | 0.72 | CD274 (0.44) | NR4A2CD274PDCD1 | |
| SCHEMBL6241638 | 0.72 | MAPK1 (0.55) | LMNAMMEITGB1ITGA5MAPK1 | |
| SCHEMBL28047824 | 0.72 | CD274 (0.41) | NR4A2CD274PDCD1 | |
| SCHEMBL6241008 | 0.69 | SCN9A (0.50) | NR4A2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4316479 | 0.68 | SMN1; SMN2 (0.36) | SMN1; SMN2PKMLMNAMMEALDH1A1 | |
| SCHEMBL16017645 | 0.68 | GABRR1 (0.38) | NR4A2SMN1; SMN2PKMFOLH1 | |
| SCHEMBL4316481 | 0.68 | SMN1; SMN2 (0.36) | SMN1; SMN2PKMLMNAMMEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311259-B1 | PHARMACEUTICAL COMPOSITION COMPRISING AN ESTER OF 5-AMINOLEVULINIC ACID AS PHOTOCHEMOTHERAPEUTIC AGENT AND A MUCOADHESIVE AGENT | PHOTOCURE ASA (NO) | 2005-06-15 | — | — | EP | claimed |