Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047732 | 0.83 | TYR (0.39) | TYR | |
| SCHEMBL30578849 | 0.75 | ALOX15 (0.47) | CD274PDCD1NR4A2MEN1CYP3A4 | |
| SCHEMBL29102647 | 0.75 | ALOX15 (0.47) | CD274PDCD1NR4A2MEN1CYP3A4 | |
| SCHEMBL31542039 | 0.75 | MEP1B (0.40) | CD274PDCD1NR4A2 | |
| SCHEMBL20999185 | 0.73 | CD274 (0.54) | CD274PDCD1 | |
| SCHEMBL28047704 | 0.73 | CD274 (0.57) | CD274PDCD1MEN1KMT2A | |
| SCHEMBL28047702 | 0.73 | CD274 (0.57) | CD274PDCD1MEN1KMT2A | |
| SCHEMBL9462879 | 0.72 | ERCC1 (0.59) | CD274PDCD1MEN1CYP3A4PTGS1 | |
| SCHEMBL6237751 | 0.72 | NR4A2 (0.37) | CD274PDCD1NR4A2 | |
| SCHEMBL29141118 | 0.71 | CD274 (0.44) | CD274PDCD1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | claimed |
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |