⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213858 | 0.77 | — | — | |
| SCHEMBL9340428 | 0.74 | NOTUM (0.33) | — | |
| SCHEMBL3655706 | 0.71 | — | — | |
| SCHEMBL3658317 | 0.71 | HPGD (0.35) | — | |
| SCHEMBL2804217 | 0.70 | HTR2A (0.34) | — | |
| SCHEMBL3282414 | 0.70 | NOTUM (0.41) | — | |
| SCHEMBL6374821 | 0.67 | GAA (0.31) | — | |
| SCHEMBL3345821 | 0.67 | PTGDR2 (0.39) | — | |
| SCHEMBL272098 | 0.66 | KDM4E (0.35) | — | |
| SCHEMBL7108455 | 0.62 | NOTUM (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180163250-A1 | Screening Broths Comprising Esculatin Compounds for the Detection of Specific Microorganisms | NEOGEN EUROPE, LTD. (GB) | 2018-06-14 | — | — | US | claimed |
| WO-2005017485-A2 | MULTIPLEX ENZYME-LINKED IMMUNOSORBENT ASSAY FOR DETECTING MULTIPLE ANALYTES | AGDIA, INC. (US) | 2005-02-24 | — | — | WO | claimed |
| US-20040241776-A1 | Multiplex enzyme-linked immunosorbent assay for detecting multiple analytes | AGDIA, INC. | 2004-12-02 | — | — | US | claimed |
| EP-0922112-A4 | FORMAZAN-BASED IMMUNOASSAY | KIRKEGAARD & PERRY LAB INC (US) | 2000-07-12 | — | — | EP | claimed |
| EP-0971037-A2 | Stable reagent for formazan-based assay | Kirkegaard & Perry Laboratories, Inc. (US) | 2000-01-12 | — | — | EP | claimed |
| US-5916746-A | POLYNUCLEOTIDE HYBRIDIZATION WHEREIN PRESENCE IN A SAMPLE OF A TARGET POLYNUCLEOTIDE MOLECULE IS DETERMINED BY A DETECTION SYSTEM COMPRISING A POLYNUCLEOTIDE PROBE WHICH HYBRIDIZES TO SAID TARGET AND A REPORTER MOLECULE COMPRISING AN ENZYME | KIRKEGAARD & PERRY LABORATORIES, INC. (US) | 1999-06-29 | — | — | US | claimed |
| EP-0922112-A1 | FORMAZAN-BASED IMMUNOASSAY | Kirkegaard & Perry Laboratories, Inc. (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1997042342-A1 | FORMAZAN-BASED IMMUNOASSAY | KIRKEGAARD & PERRY LABORATORIES, INC. (US) | 1997-11-13 | — | — | WO | claimed |
| EP-0415983-B1 | ASSAY DEVICE AND IMMUNOASSAY | DU PONT (US) | 1995-11-22 | — | — | EP | claimed |
| US-5443958-A | 2-acrylamine-2-methyl-1-propanesulfonic acid enhancement of alkaline phosphatase label detection | DIRECTOR-GENERAL, NATIONAL INSTITUTE OF ANIMAL INDUSTRY (JP) | 1995-08-22 | — | — | US | claimed |
| US-5391478-A | Assay device and immunoassay | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-02-21 | — | — | US | claimed |
| US-5137804-A | ASSAY DEVICE AND IMMUNOASSAY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-11 | — | — | US | claimed |
| US-20180163250-A1 | Screening Broths Comprising Esculatin Compounds for the Detection of Specific Microorganisms | NEOGEN EUROPE, LTD. (GB) | 2018-06-14 | — | — | US | disclosed |
| CN-101928728-B | Preparation method and application of enterovirus-like virus particles | HU YUCHENG | 2013-03-27 | — | — | CN | disclosed |
| CN-101928728-A | Preparation method and application of enterovirus-like virus particles | YUCHENG HU | 2010-12-29 | — | — | CN | disclosed |
| WO-2005017485-A2 | MULTIPLEX ENZYME-LINKED IMMUNOSORBENT ASSAY FOR DETECTING MULTIPLE ANALYTES | AGDIA, INC. (US) | 2005-02-24 | — | — | WO | disclosed |
| US-4772584-A | CLEAVAGE OF SIX AMINO ACID PEPTIDE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1988-09-20 | — | — | US | disclosed |
| WO-1988003032-A1 | DIAGNOSIS OF AND VACCINE FOR JAPANESE ENCEPHALITIS VIRUS AND RELATED VIRUSES | FOURNIER MAURIELLE J (US) | 1988-05-05 | — | — | WO | disclosed |
| WO-1987007146-A1 | INHIBITOR OF C5a-MEDIATED CHEMOTAXIS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1987-12-03 | — | — | WO | disclosed |
| WO-1987006264-A1 | EXPRESSION OF THE CLONED LYSOSTAPHIN GENE | PUBLIC HEALTH RESEARCH INSTITUTE OF THE CITY OF NE (US) | 1987-10-22 | — | — | WO | disclosed |