SCHEMBL2804217

SCHEMBL2804217

Cn1cc(O)c2c(Cl)c(Br)ccc21

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.34
HTR2C P28335 4/20 0.34
HTR2B P41595 4/20 0.34
MEN1 O00255 4/20 0.33
ALDH1A1 P00352 4/20 0.33
MAPT P10636 4/20 0.33
HPGD P15428 4/20 0.33
KMT2A Q03164 4/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALOX12 P18054 1/20 0.32
CA9 Q16790 1/20 0.32
IDE P14735 1/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
APAF1 O14727 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3282414 0.78 NOTUM (0.41) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL11213858 0.73
SCHEMBL5708911 0.73 AKR1C3 (0.39) ALDH1A1MAPTHPGD
SCHEMBL3437628 0.73 CFD (0.33) ALDH1A1HPGDGAAALOX12
SCHEMBL3345821 0.71 PTGDR2 (0.39) ALDH1A1MAPTKMT2A
SCHEMBL23937812 0.70 HTR2A (0.46) HTR2AHTR2CHTR2BALDH1A1MAPT
SCHEMBL6238088 0.70
SCHEMBL434728 0.70 MCL1 (0.39)
SCHEMBL25672739 0.68 HTR2A (0.37) HTR2AHTR2CHTR2B
SCHEMBL23500530 0.66 NR3C1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10808275-B2 Use of at least one chromogenic and/or fluorogenic phosphatase substrate for the detection and/or enumeration of enterobacteria in a sample bioMérieux (FR) 2020-10-20 US disclosed
EP-2877591-B1 METHOD OF DETECTING OXA-048 CARBAPENEMASE PRODUCING BACTERIA BIOMERIEUX SA (FR) 2018-01-10 EP disclosed
EP-2689026-B1 DETECTION OF BACTERIA HAVING A RESISTANCE TO CARBAPENEMS BIOMERIEUX SA (FR) 2017-03-08 EP disclosed
US-9562899-B2 Method of detecting OXA-048 carbapenemase producing bacteria bioMérieux (FR) 2017-02-07 US disclosed
US-9347888-B2 Detection of bacteria exhibiting a resistance to carbapenems BIOMERIEUX (FR) 2016-05-24 US disclosed
US-20160046976-A1 USE OF AT LEAST ONE CHROMOGENIC AND/OR FLUOROGENIC PHOSPHATASE SUBSTRATE FOR THE DETECTION AND/OR ENUMERATION OF ENTEROBACTERIA IN A SAMPLE BIOMERIEUX (FR) 2016-02-18 US disclosed
EP-2981619-A1 USE OF AT LEAST ONE CHROMOGENIC AND/OR FLUOROGENIC PHOSPHATASE SUBSTRATE FOR THE DETECTION AND/OR ENUMERATION OF ENTEROBACTERIA IN A SAMPLE Biomérieux (FR) 2016-02-10 EP disclosed
US-20150160211-A1 METHOD OF DETECTING OXA-048 CARBAPENEMASE PRODUCING BACTERIA BIOMERIEUX (FR) 2015-06-11 US disclosed
EP-2877591-A1 METHOD OF DETECTING OXA-048 CARBAPENEMASE PRODUCING BACTERIA Biomérieux (FR) 2015-06-03 EP disclosed
WO-2014161864-A1 USE OF AT LEAST ONE CHROMOGENIC AND/OR FLUOROGENIC PHOSPHATASE SUBSTRATE FOR THE DETECTION AND/OR ENUMERATION OF ENTEROBACTERIA IN A SAMPLE bioMérieux (FR) 2014-10-09 WO disclosed
CN-101631875-A Be used to detect and/or differentiate the medium of bacterium BIOMERIEUX SA 2010-01-20 CN disclosed
EP-2142662-A2 REACTION MEDIUM FOR IDENTIFYING/DETECTING MICRO-ORGANISMS bioMérieux (FR) 2010-01-13 EP disclosed
EP-2111461-A2 BACTERIA DETECTION AND/OR IDENTIFICATION MEDIUM BIOMERIEUX (FR) 2009-10-28 EP disclosed
EP-2111462-A2 MEDIUM FOR DETECTING AND/OR IDENTIFYING BACTERIA BIOMERIEUX (FR) 2009-10-28 EP disclosed
EP-2111460-A2 MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA BIOMERIEUX (FR) 2009-10-28 EP disclosed
WO-2009056762-A2 BIOCHEMICAL TEST FOR CONFIRMING THE PRESENCE OF L. MONOCYTOGENES bioMérieux (FR) 2009-05-07 WO disclosed
WO-2008148972-A2 REACTION MEDIUM FOR IDENTIFYING/DETECTING MICRO-ORGANISMS bioMérieux (FR) 2008-12-11 WO disclosed
WO-2008104680-A2 MEDIUM FOR DETECTING AND/OR IDENTIFYING BACTERIA bioMérieux (FR) 2008-09-04 WO disclosed
WO-2008104681-A2 BACTERIA DETECTION AND/OR IDENTIFICATION MEDIUM bioMérieux (FR) 2008-09-04 WO disclosed
WO-2008104679-A2 MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA bioMérieux (FR) 2008-09-04 WO disclosed