Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 18/20 | 0.84 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531754 | 0.81 | KIF11 (1.00) | KIF11CA1CA2 | |
| SCHEMBL1645153 | 0.79 | CA1 (1.00) | KIF11CA1CA2 | |
| SCHEMBL6257183 | 0.78 | KIF11 (0.65) | KIF11CA1CA2KDM1AMAOB | |
| SCHEMBL6240077 | 0.77 | KIF11 (0.55) | KIF11KDM1AMAOB | |
| SCHEMBL23226495 | 0.76 | KIF11 (0.56) | KIF11 | |
| SCHEMBL28530523 | 0.74 | KIF11 (0.61) | KIF11KDM1AMAOB | |
| SCHEMBL29690424 | 0.74 | KIF11 (0.61) | KIF11KDM1AMAOB | |
| SCHEMBL6235808 | 0.74 | KIF11 (0.65) | KIF11CA1CA2 | |
| SCHEMBL18078706 | 0.72 | KDM1A (0.57) | KIF11KDM1AMAOB | |
| SCHEMBL4342508 | 0.72 | KIF11 (0.59) | KIF11KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |