Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | FABP1 | P07148 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245446 | 0.90 | NR1H4 (0.47) | NR1H4PPARDFABP1FABP4ALKBH1 | |
| SCHEMBL3499309 | 0.90 | NR1H4 (0.58) | NR1H4PPARDSMN1; SMN2FABP1FABP4 | |
| SCHEMBL29435095 | 0.84 | ITGA4 (0.53) | HPGDSMN1; SMN2KDM4ERAB9ANPSR1 | |
| SCHEMBL10565484 | 0.84 | NR1H4 (0.53) | NR1H4PPARDSMN1; SMN2FABP1FABP4 | |
| SCHEMBL29576251 | 0.84 | HPGD (0.50) | HPGDSMN1; SMN2KDM4ERAB9ANPSR1 | |
| SCHEMBL6240957 | 0.82 | NR1H4 (0.52) | NR1H4PPARD | |
| SCHEMBL15085666 | 0.81 | PTPN1 (0.55) | HPGDSMN1; SMN2KDM4ERAB9ANPSR1 | |
| SCHEMBL19715977 | 0.81 | PTPN1 (0.55) | HPGDSMN1; SMN2KDM4ERAB9ANPSR1 | |
| SCHEMBL15380599 | 0.81 | SMN1; SMN2 (0.56) | HPGDSMN1; SMN2KDM4ERAB9ANPSR1 | |
| SCHEMBL2088391 | 0.80 | MAOB (0.44) | HPGDSMN1; SMN2KDM4ERAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |