SCHEMBL6238618

SCHEMBL6238618

Cc1ccc(C2=CC=CC2=O)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
CYP2C19 P33261 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37
PKM P14618 1/20 0.37
MAPK1 P28482 1/20 0.37
MCL1 Q07820 1/20 0.37
HSD17B3 P37058 1/20 0.35
ACHE P22303 1/20 0.35
MGLL Q99685 1/20 0.34
LMNA P02545 2/20 0.33
ALDH1A1 P00352 2/20 0.33
RGS4 P49798 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28701270 0.78 MAPT (0.35) HPGDHSD17B10TDP1MEN1KMT2A
SCHEMBL28352043 0.78 MGAM (0.44) HPGDALOX15HSD17B10TDP1MEN1
SCHEMBL28703413 0.78 KDM4E (0.65) TDP1MEN1KMT2AMAPTKDM4E
SCHEMBL27626616 0.77 MAOA (0.56) HPGDHSD17B10MAPTKDM4EMAPK1
SCHEMBL28711805 0.77 TDP1 (0.46) HPGDALOX15HSD17B10TDP1MEN1
SCHEMBL28936760 0.77 TDP1 (0.46) HPGDALOX15HSD17B10TDP1MEN1
SCHEMBL3786541 0.74 KDM4E (0.66) CYP2D6CYP2C9HPGDALOX15CYP2C19
SCHEMBL3883020 0.72
SCHEMBL3885051 0.72
SCHEMBL28720088 0.72 APP (0.44) HSD17B10MAPTMAPK1ACHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108358767-A The double fluorine monomers of methylbenzene containing pentaphene, preparation method and its application in poly(aryl ether ketone) functional membrane 吉林大学 2018-08-03 CN disclosed
EP-1546217-A1 PENTAARYLCYCLOPENTADIENYL UNITS AS ACTIVE UNITS IN RESISTIVE MEMORY ELEMENTS Infineon Technologies AG (DE) 2005-06-29 EP disclosed
WO-2004031247-A1 PENTAARYLCYCLOPENTADIENYL UNITS AS ACTIVE UNITS IN RESISTIVE MEMORY ELEMENTS INFINEON TECHNOLOGIES AG (DE) 2004-04-15 WO disclosed