Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 15/20 | 0.78 |
| ▸ | RARB | P10826 | 16/20 | 0.66 |
| ▸ | RARG | P13631 | 12/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239094 | 0.91 | RARA (0.69) | RARARARBRARG | |
| SCHEMBL6232866 | 0.89 | RARA (0.77) | RARARARBRARGMAPT | |
| SCHEMBL6237886 | 0.88 | RARA (1.00) | RARARARBRARG | |
| SCHEMBL27463421 | 0.82 | RARA (0.58) | RARARARBRARGMAPT | |
| SCHEMBL6233016 | 0.82 | RARA (0.58) | RARARARBRARG | |
| SCHEMBL6234835 | 0.82 | RARA (0.81) | RARARARBRARG | |
| SCHEMBL27461633 | 0.80 | RARA (0.64) | RARARARBRARGMAPT | |
| SCHEMBL6235176 | 0.80 | RARB (0.63) | RARARARBRARGMAPT | |
| SCHEMBL6239917 | 0.80 | RARB (1.00) | RARARARBRARG | |
| SCHEMBL7635590 | 0.78 | RARB (0.55) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1535919-A2 | Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities | Allergan, Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| EP-0991636-A1 | SYNTHESIS AND USE OF RETINOID COMPOUNDS HAVING NEGATIVE HORMONE AND/OR ANTAGONIST ACTIVITIES | Allergan Sales, Inc. (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998058922-A1 | SYNTHESIS AND USE OF RETINOID COMPOUNDS HAVING NEGATIVE HORMONE AND/OR ANTAGONIST ACTIVITIES | ALLERGAN SALES, INC. (US) | 1998-12-30 | — | — | WO | disclosed |