Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 9/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.60 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.60 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.60 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.60 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.58 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.53 |
| ▸ | PLAT | P00750 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639750 | 0.89 | PTGER1 (0.57) | NR4A2NPC1RAB9AMRGPRX4PTGER1 | |
| SCHEMBL6244114 | 0.87 | PTGER1 (0.55) | NR4A2NPC1RAB9AMRGPRX4PTGER1 | |
| SCHEMBL6238338 | 0.84 | FFAR1 (0.66) | NR4A2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL7222374 | 0.80 | NR4A2 (0.68) | NR4A2NPC1RAB9AMRGPRX4NR4A1 | |
| SCHEMBL29260790 | 0.80 | FFAR1 (0.58) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL27718811 | 0.79 | FFAR1 (0.62) | NPC1RAB9APTGER1PTGER4PTGER3 | |
| SCHEMBL17088255 | 0.79 | NR4A2 (0.67) | NR4A2NPC1RAB9AMRGPRX4NR4A1 | |
| SCHEMBL4030554 | 0.79 | NR4A2 (0.67) | NR4A2NPC1RAB9AMRGPRX4NR4A1 | |
| SCHEMBL3299859 | 0.79 | MCL1 (0.57) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL6259772 | 0.79 | FFAR1 (0.74) | PTGER1PTGER4PTGER3PTGER2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |