Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 10/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.63 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17088259 | 0.89 | NR4A2 (0.69) | NR4A2NPC1RAB9ANR4A1NR4A3 | |
| SCHEMBL17089120 | 0.88 | MEN1 (0.59) | NR4A2NPC1RAB9ANR4A1NR4A3 | |
| SCHEMBL6836371 | 0.82 | MRGPRX4 (0.75) | NR4A2RAB9AKMT2AMEN1MRGPRX4 | |
| SCHEMBL17088254 | 0.81 | NR4A2 (0.58) | NR4A2NPC1RAB9ANR4A1NR4A3 | |
| SCHEMBL17088257 | 0.81 | NR4A2 (0.58) | NR4A2NPC1RAB9ANR4A1NR4A3 | |
| Hydrochloric Acid SCHEMBL6843292 | 0.81 | MRGPRX4 (0.73) | NR4A2RAB9AKMT2AMEN1MRGPRX4 | |
| SCHEMBL339009 | 0.80 | NR4A2 (1.00) | NR4A2NR4A1NR4A3KMT2AMEN1 | |
| SCHEMBL30207018 | 0.80 | NR4A2 (1.00) | NR4A2NR4A1NR4A3KMT2AMEN1 | |
| SCHEMBL4406160 | 0.80 | NR4A2 (0.87) | NR4A2RAB9AMRGPRX4SRD5A2 | |
| SCHEMBL10787479 | 0.79 | KMT2A (0.80) | NR4A2NPC1RAB9AKMT2AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139599-B1 | 2-periodic metal-organic frameworks (MOFs) as supermolecular building layers (SBLs) for making targeted 3-periodic MOFs | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-09-22 | — | — | US | disclosed |