Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.69 |
| ▸ | MEN1 | O00255 | 10/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | HBB | P68871 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25633556 | 0.87 | MAPT (0.77) | MAPTKMT2AMEN1LMNAHSD17B10 | |
| SCHEMBL11035766 | 0.81 | MAPT (1.00) | MAPTKMT2AMEN1LMNAHSD17B10 | |
| SCHEMBL10429450 | 0.80 | MEN1 (0.73) | MAPTKMT2AMEN1LMNAHSD17B10 | |
| SCHEMBL10429462 | 0.79 | MAPT (0.67) | MAPTKMT2AMEN1LMNAHSD17B10 | |
| SCHEMBL8114562 | 0.78 | KMT2A (1.00) | MAPTKMT2AMEN1LMNAALOX15 | |
| SCHEMBL5341408 | 0.77 | MAPT (0.62) | MAPTKMT2AMEN1LMNAHSD17B10 | |
| SCHEMBL5394498 | 0.76 | MEN1 (0.73) | MAPTKMT2AMEN1LMNAHSD17B10 | |
| SCHEMBL8140374 | 0.76 | MEN1 (0.60) | MAPTKMT2AMEN1LMNAHSD17B10 | |
| SCHEMBL5479900 | 0.75 | MAPT (0.60) | MAPTKMT2AMEN1LMNACASP3 | |
| SCHEMBL31717926 | 0.75 | MAPT (0.60) | MAPTKMT2AMEN1LMNACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605408-A | 5-hydroxy-1, 3-disubstituted phenyl pyrido [2,3-d ] pyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2022-06-10 | — | — | CN | disclosed |
| EP-1534239-A2 | PREPARATION OF SUBMICRON SIZED PARTICLES WITH POLYMORPH CONTROL AND NEW POLYMORPH OF ITRACONAZOLE | BAXTER INTERNATIONAL INC. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004054500-A2 | PREPARATION OF SUBMICRON SIZED PARTICLES WITH POLYMORPH CONTROL AND NEW POLYMORPH OF ITRACONAZOLE | BAXTER INTERNATIONAL INC. (US) | 2004-07-01 | — | — | WO | disclosed |
| US-20030096013-A1 | Preparation of submicron sized particles with polymorph control | BAXTER INTERNATIONAL INC. | 2003-05-22 | — | — | US | disclosed |
| US-4382983-A | PARTIALLY HYDROLYZED SILOXANE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-10 | — | — | US | disclosed |