SCHEMBL10429462

SCHEMBL10429462

O=C1CC(=O)N(c2ccccc2Cl)C(=O)N1

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.67
MEN1 O00255 8/20 0.67
KMT2A Q03164 8/20 0.67
ALOX12 P18054 2/20 0.67
LMNA P02545 1/20 0.64
MGLL Q99685 1/20 0.50
HSD17B10 Q99714 3/20 0.48
ALOX15 P16050 1/20 0.48
HBB P68871 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.46
ALOX5 P09917 2/20 0.46
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6238897 0.79 MAPT (1.00) MAPTMEN1KMT2AALOX12LMNA
SCHEMBL8117328 0.78 MAPT (0.61) MAPTMEN1KMT2AMGLLHSD17B10
SCHEMBL11035766 0.78 MAPT (1.00) MAPTMEN1KMT2AALOX12LMNA
SCHEMBL5341408 0.77 MAPT (0.62) MAPTMEN1KMT2AALOX12LMNA
SCHEMBL8140374 0.76 MEN1 (0.60) MAPTMEN1KMT2AALOX12LMNA
SCHEMBL11133610 0.75 HPGD (0.62) MAPTMEN1KMT2AALOX12MGLL
SCHEMBL9354455 0.74 MAPT (0.59) MAPTMEN1KMT2AALOX12LMNA
SCHEMBL125016 0.74 MEN1 (0.68) MAPTMEN1KMT2ALMNAHSD17B10
SCHEMBL5455707 0.74 ALOX5 (0.51) MAPTMEN1KMT2AALOX12LMNA
SCHEMBL3786268 0.74 MGLL (0.61) MAPTMEN1KMT2AMGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4942225-A Preparation of diazo and azo compounds using azidoformamidium salts BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed