Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240043 | 0.89 | PTGER1 (0.40) | BCHECYP4F2CYP4A11 | |
| SCHEMBL2986841 | 0.85 | BCHE (0.44) | BCHEACHELTA4HDHFRCYP4F2 | |
| SCHEMBL6242841 | 0.85 | CYP4F2 (0.44) | BCHEACHELTA4HMAOBCYP4F2 | |
| SCHEMBL6241365 | 0.85 | SLC1A5 (0.41) | DHFRLTB4R2 | |
| SCHEMBL13009803 | 0.82 | BCHE (0.42) | BCHEACHELTA4HDHFRPPARD | |
| SCHEMBL13009683 | 0.82 | ALOX5 (0.43) | BCHEACHELTA4H | |
| SCHEMBL13009892 | 0.81 | BCHE (0.45) | BCHEACHELTA4HLTB4RLTB4R2 | |
| SCHEMBL13009700 | 0.81 | BCHE (0.45) | BCHEACHELTA4HLTB4RLTB4R2 | |
| SCHEMBL13009695 | 0.81 | BCHE (0.45) | BCHEACHELTA4HLTB4RLTB4R2 | |
| SCHEMBL6240093 | 0.80 | PTGER1 (0.40) | BCHEACHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216225-B1 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER HEALTHCARE AG (DE) | 2005-07-06 | — | — | EP | disclosed |